InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cblc

Summary

InnateDB Protein

IDBP-264512.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cblc

Protein Name

Casitas B-lineage lymphoma c

Synonyms

2310076I21Rik; 2310079L19Rik; Cbl3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000104088

InnateDB Gene

IDBG-152552 (Cblc)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	33 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001784	phosphotyrosine binding
GO:0004842	ubiquitin-protein transferase activity
GO:0004871	signal transducer activity
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0007166	cell surface receptor signaling pathway
GO:0016567	protein ubiquitination
GO:0023051	regulation of signaling

Cellular Component

GO:0000151	ubiquitin ligase complex
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

MGI:1931457

InterPro

IPR000980 SH2 domain
IPR003153 Adaptor protein Cbl, N-terminal helical
IPR014741 Adaptor protein Cbl, EF hand-like
IPR014742 Adaptor protein Cbl, SH2-like

PFAM

PF00017
PF14633
PF02262
PF02761
PF02762

PRINTS

PR00401

PIRSF

SMART

SM00252

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt