InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Foxn1

Summary

InnateDB Protein

IDBP-264852.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Foxn1

Protein Name

forkhead box N1

Synonyms

D11Bhm185e; Fkh19; HFH-11; Hfh11; nu; nude; Whn;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103929

InnateDB Gene

IDBG-202803 (Foxn1)

Protein Structure

UniProt Annotation

Function

Transcriptional regulator involved in development.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Expressed in thymus and skin.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003690	double-stranded DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0008134	transcription factor binding
GO:0008301	DNA binding, bending
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001942	hair follicle development
GO:0002260	lymphocyte homeostasis
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0007389	pattern specification process
GO:0008283	cell proliferation
GO:0008544	epidermis development
GO:0030216	keratinocyte differentiation
GO:0033081	regulation of T cell differentiation in thymus
GO:0035878	nail development
GO:0048538	thymus development
GO:0050673	epithelial cell proliferation
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity