Version 5.4
Mus musculus Protein: Fbxo27
Summary
InnateDB Protein IDBP-264872.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo27
Protein Name F-box protein 27
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000103916
InnateDB Gene IDBG-163995 (Fbxo27)
Protein Structure
UniProt Annotation
Function Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind complex-type oligosaccharides. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Detected in brain, heart and muscle. {ECO:0000269PubMed:18203720}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001948 glycoprotein binding
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0019005 SCF ubiquitin ligase complex
Protein Structure and Domains
PDB ID MGI:2685007
InterPro IPR001810 F-box domain
IPR007397 F-box associated (FBA) domain
IPR008979 Galactose-binding domain-like
PFAM PF00646
PF12937
PF13013
PF04300
PRINTS
PIRSF
SMART SM00256
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6DIA9
PhosphoSite PhosphoSite-
TrEMBL Q3TEI7
UniProt Splice Variant
Entrez Gene 233040
UniGene Mm.116116
RefSeq NP_001157174
MGI ID
MGI Symbol Fbxo27
OMIM
CCDS CCDS52164
HPRD
IMGT
EMBL AC109162 AK053292 AK140275 AK158463 AK169614 BC075656
GenPept AAH75656 BAC35334 BAE24311 BAE34522 BAE41261

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca