Version 5.4
Mus musculus Gene: Fbxo27
Summary
InnateDB Gene IDBG-163995.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo27
Gene Name F-box protein 27
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037463
Encoded Proteins
IDBP-163997
F-box protein 27
IDBP-264872
F-box protein 27
IDBP-264874
F-box protein 27
IDBP-539681
F-box protein 27
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161243:
Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:28692849-28699338
Strand Forward strand
Band B1
Transcripts
ENSMUST00000039998 ENSMUSP00000038432
ENSMUST00000108281 ENSMUSP00000103916
ENSMUST00000108280 ENSMUSP00000103915
ENSMUST00000151227 ENSMUSP00000116838
ENSMUST00000127368
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001948 glycoprotein binding
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0019005 SCF ubiquitin ligase complex
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000161243
View Gene Order
Pathways
NETPATH
REACTOME
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_230745
Immune System pathway
REACT_199115
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_229531
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.116116
RefSeq NM_001163702 NM_207238 XM_006539862 XM_006539863 XM_006539864 XM_006539866 XM_006539867
OMIM
CCDS CCDS21051 CCDS52164
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca