InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gabrr2

Summary

InnateDB Protein

IDBP-265123.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gabrr2

Protein Name

gamma-aminobutyric acid (GABA) C receptor, subunit rho 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103797

InnateDB Gene

IDBG-134359 (Gabrr2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004890	GABA-A receptor activity
GO:0005230	extracellular ligand-gated ion channel activity
GO:0005254	chloride channel activity
GO:0019904	protein domain specific binding

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006821	chloride transport
GO:0007214	gamma-aminobutyric acid signaling pathway
GO:0007601	visual perception
GO:0034220	ion transmembrane transport
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0030424	axon
GO:0034707	chloride channel complex
GO:0045202	synapse
GO:0045211	postsynaptic membrane

Protein Structure and Domains

PDB ID

MGI:95626

InterPro

IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding
IPR008057 Gamma-aminobutyric-acid A receptor, Rho
IPR008059 Gamma-aminobutyric-acid A receptor, Rho2

PFAM

PF02932
PF02931

PRINTS

PR00253
PR00252
PR01670
PR01672

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P56476