Mus musculus Protein: Tbx4
Summary
InnateDB Protein IDBP-265360.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbx4
Protein Name T-box 4
Synonyms 3930401C23;
Species Mus musculus
Ensembl Protein ENSMUSP00000103682
InnateDB Gene IDBG-206728 (Tbx4)
Protein Structure
UniProt Annotation
Function Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00201}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0001525 angiogenesis
GO:0002009 morphogenesis of an epithelium
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0030324 lung development
GO:0030326 embryonic limb morphogenesis
GO:0035108 limb morphogenesis
GO:0048705 skeletal system morphogenesis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:102556
InterPro IPR001699 Transcription factor, T-box
IPR008967 p53-like transcription factor, DNA-binding
PFAM PF00907
PRINTS PR00937
PIRSF
SMART SM00425
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P70325
PhosphoSite PhosphoSite-P70325
TrEMBL Q8BSY3
UniProt Splice Variant
Entrez Gene 21387
UniGene Mm.275336
RefSeq XP_006532842
MGI ID
MGI Symbol Tbx4
OMIM
CCDS CCDS25196
HPRD
IMGT
EMBL AK028407 AK147984 AL592465 AY075134 CH466556 U57329
GenPept AAC53108 AAL77209 BAC25935 BAE28267 CAI25365 EDL15777