InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ccne1

Summary

InnateDB Protein

IDBP-265403.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ccne1

Protein Name

cyclin E1

Synonyms

AW538188; CycE1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103658

InnateDB Gene

IDBG-175446 (Ccne1)

Protein Structure

UniProt Annotation

Function

Essential for the control of the cell cycle at the G1/S (start) transition.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Found in adult spleen, and to a lesser extent in adult testis and brain.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 78 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	16 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	78 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016301	kinase activity
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
GO:0019901	protein kinase binding

Biological Process

GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082	G1/S transition of mitotic cell cycle
GO:0006270	DNA replication initiation
GO:0006468	protein phosphorylation
GO:0016055	Wnt signaling pathway
GO:0045859	regulation of protein kinase activity
GO:0051301	cell division
GO:0051726	regulation of cell cycle