InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Klk6

Summary

InnateDB Protein

IDBP-265563.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Klk6

Protein Name

kallikrein related-peptidase 6

Synonyms

AI849898; BSP; Bssp; Klk29; MSP; neurosin; Prss18; Prss9;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103601

InnateDB Gene

IDBG-177611 (Klk6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005515	protein binding
GO:0008233	peptidase activity

Biological Process

GO:0006508	proteolysis
GO:0010975	regulation of neuron projection development
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
GO:0070997	neuron death

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0015630	microtubule cytoskeleton
GO:0030141	secretory granule
GO:0031965	nuclear membrane
GO:0045171	intercellular bridge

Protein Structure and Domains

PDB ID

MGI:1343166

InterPro

IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR015420 Peptidase S1A, nudel

PFAM

PF00089
PF09342

PRINTS

PR00722

PIRSF

SMART

SM00020

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt