Version 5.4
Mus musculus Protein: Unc13b
Summary
InnateDB Protein IDBP-265585.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Unc13b
Protein Name unc-13 homolog B (C. elegans)
Synonyms Munc13-1; Munc13-2; Unc13a; Unc13h1; Unc13h2;
Species Mus musculus
Ensembl Protein ENSMUSP00000103587
InnateDB Gene IDBG-140233 (Unc13b)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001566 non-kinase phorbol ester receptor activity
GO:0005515 protein binding
GO:0019992 diacylglycerol binding
GO:0046872 metal ion binding
Biological Process
GO:0007268 synaptic transmission
GO:0007528 neuromuscular junction development
GO:0016081 synaptic vesicle docking involved in exocytosis
GO:0016082 synaptic vesicle priming
GO:0035249 synaptic transmission, glutamatergic
GO:0035556 intracellular signal transduction
GO:0048172 regulation of short-term neuronal synaptic plasticity
GO:0060384 innervation
Cellular Component
GO:0031594 neuromuscular junction
Protein Structure and Domains
PDB ID MGI:1342278
InterPro IPR000008 C2 domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding
IPR010439 Calcium-dependent secretion activator
IPR019558 Mammalian uncoordinated homology 13, subgroup, domain 2
PFAM PF00168
PF00130
PF06292
PF10540
PRINTS PR00360
PIRSF
SMART SM00239
SM00109
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q263
UniProt Splice Variant
Entrez Gene 22249
UniGene
RefSeq XP_006537854
MGI ID
MGI Symbol Unc13b
OMIM
CCDS
HPRD
IMGT
EMBL AL672276 AL732504 AL772176
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca