InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Shank1

Summary

InnateDB Protein

IDBP-265622.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Shank1

Protein Name

SH3/ankyrin domain gene 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103567

InnateDB Gene

IDBG-178618 (Shank1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0032232

negative regulation of actin filament bundle assembly

Cellular Component

GO:0045211

postsynaptic membrane

Protein Structure and Domains

PDB ID

MGI:3613677

InterPro

IPR001452 SH3 domain
IPR001478 PDZ domain
IPR001660 Sterile alpha motif domain
IPR002110 Ankyrin repeat
IPR011510 Sterile alpha motif, type 2
IPR011511 Variant SH3 domain
IPR013761 Sterile alpha motif/pointed domain
IPR020683 Ankyrin repeat-containing domain
IPR021129 Sterile alpha motif, type 1

PFAM