InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Shank1

Summary

InnateDB Gene

IDBG-178618.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Shank1

Gene Name

SH3/ankyrin domain gene 1

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000038738

Encoded Proteins

IDBP-265618

SH3/ankyrin domain gene 1

IDBP-265620

SH3/ankyrin domain gene 1

IDBP-265622

SH3/ankyrin domain gene 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161681:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:44310253-44358351

Strand

Forward strand

Band

Transcripts

ENSMUST00000107938	ENSMUSP00000103571
ENSMUST00000107935	ENSMUSP00000103568
ENSMUST00000107934	ENSMUSP00000103567
ENSMUST00000134470
ENSMUST00000134205
ENSMUST00000154776
ENSMUST00000127164

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0017124	SH3 domain binding
GO:0030159	receptor signaling complex scaffold activity
GO:0030160	GKAP/Homer scaffold activity
GO:0031877	somatostatin receptor binding
GO:0032403	protein complex binding
GO:0035255	ionotropic glutamate receptor binding
GO:0042802	identical protein binding
GO:0071532	ankyrin repeat binding
GO:0097110	scaffold protein binding

Biological Process

GO:0006461	protein complex assembly
GO:0007616	long-term memory
GO:0008306	associative learning
GO:0030534	adult behavior
GO:0032232	negative regulation of actin filament bundle assembly
GO:0035176	social behavior
GO:0035418	protein localization to synapse
GO:0042048	olfactory behavior
GO:0046959	habituation
GO:0050885	neuromuscular process controlling balance
GO:0050894	determination of affect
GO:0060013	righting reflex
GO:0060074	synapse maturation
GO:0060997	dendritic spine morphogenesis
GO:0060999	positive regulation of dendritic spine development
GO:0071625	vocalization behavior
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000463	positive regulation of excitatory postsynaptic membrane potential

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0008328	ionotropic glutamate receptor complex
GO:0016020	membrane
GO:0017146	N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054	cell junction
GO:0030425	dendrite
GO:0043005	neuron projection
GO:0043197	dendritic spine
GO:0045202	synapse
GO:0045211	postsynaptic membrane
GO:0060076	excitatory synapse
GO:0097481	neuronal postsynaptic density

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000161681

View Gene Order

ENSBTAG00000013107

Not yet available

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.360368 Mm.397655 Mm.449086

RefSeq

NM_001034115 XM_006540864 XM_006540865 XM_006540866 XM_006540867 XM_006540868 XM_006540871 XM_006540872 XM_006540873 XM_006540874 XM_006540875 XM_006540876

OMIM

CCDS

CCDS52229

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas