InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mesp2

Summary

InnateDB Protein

IDBP-266779.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Mesp2

Protein Name

mesoderm posterior 2

Synonyms

bHLHc6;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103017

InnateDB Gene

IDBG-194351 (Mesp2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0046983	protein dimerization activity

Biological Process

GO:0001756	somitogenesis
GO:0007219	Notch signaling pathway
GO:0008078	mesodermal cell migration
GO:0023019	signal transduction involved in regulation of gene expression
GO:0032525	somite rostral/caudal axis specification
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1096325

InterPro

IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain

PFAM

PF00010

PRINTS

PIRSF

SMART

SM00353

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

MGI ID

MGI Symbol

OMIM

CCDS

HPRD

IMGT

EMBL

AC109221 BC145652 BC145654 CH466543

GenPept

AAI45653 AAI45655 EDL07045

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca