Version 5.4
Mus musculus Protein: Ptprd
Summary
InnateDB Protein IDBP-266980.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptprd
Protein Name protein tyrosine phosphatase, receptor type, D
Synonyms 1110002J03Rik; 3000002J10Rik; B230219D21Rik; R-PTP-delta;
Species Mus musculus
Ensembl Protein ENSMUSP00000102910
InnateDB Gene IDBG-158837 (Ptprd)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity Brain, kidney, heart, and some B-cell lines.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0016791 phosphatase activity
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0006470 protein dephosphorylation
GO:0007157 heterophilic cell-cell adhesion
GO:0016311 dephosphorylation
GO:0030182 neuron differentiation
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0050775 positive regulation of dendrite morphogenesis
GO:0097105 presynaptic membrane assembly
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:97812
InterPro IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR029021 Protein-tyrosine phosphatase-like
PFAM PF00102
PF00041
PF01108
PF07679
PRINTS PR00700
PIRSF
SMART SM00194
SM00404
SM00408
SM00409
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q64487
PhosphoSite PhosphoSite-Q64487
TrEMBL Q8R169
UniProt Splice Variant
Entrez Gene 19266
UniGene Mm.489068
RefSeq XP_006537754
MGI ID
MGI Symbol Ptprd
OMIM
CCDS
HPRD
IMGT
EMBL AF326559 AF326560 AK033873 AK034067 AK043201 AK138585 AL844848 AL845158 AL845333 AL845335 AL845496 AL845508 AL845517 AL928625 AL928645 AL929181 AL929553 AL954189 AL954376 AL954675 BC025145 BX296523 BX649450 D13903 D13904 D13905 Z23051
GenPept AAH25145 AAL37405 AAL37406 BAA03003 BAA03004 BAA03005 BAC28503 BAC28569 BAC31488 BAE23705 CAA80586

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca