Version 5.4
Mus musculus Gene: Ptprd
Summary
InnateDB Gene IDBG-158837.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptprd
Gene Name protein tyrosine phosphatase, receptor type, D
Synonyms 1110002J03Rik; 3000002J10Rik; B230219D21Rik; R-PTP-delta
Species Mus musculus
Ensembl Gene ENSMUSG00000028399
Encoded Proteins
IDBP-158839
protein tyrosine phosphatase, receptor type, D
IDBP-158841
protein tyrosine phosphatase, receptor type, D
IDBP-158843
protein tyrosine phosphatase, receptor type, D
IDBP-266980
protein tyrosine phosphatase, receptor type, D
IDBP-626503
protein tyrosine phosphatase, receptor type, D
IDBP-626504
protein tyrosine phosphatase, receptor type, D
IDBP-626505
protein tyrosine phosphatase, receptor type, D
IDBP-626508
protein tyrosine phosphatase, receptor type, D
IDBP-626509
protein tyrosine phosphatase, receptor type, D
IDBP-626511
protein tyrosine phosphatase, receptor type, D
IDBP-626512
protein tyrosine phosphatase, receptor type, D
IDBP-626513
protein tyrosine phosphatase, receptor type, D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000153707:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:75941238-78211961
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000102834 ENSMUSP00000099898
ENSMUST00000098005 ENSMUSP00000095614
ENSMUST00000050757 ENSMUSP00000058466
ENSMUST00000084467
ENSMUST00000107289 ENSMUSP00000102910
ENSMUST00000107287
ENSMUST00000156656
ENSMUST00000138955
ENSMUST00000140422
ENSMUST00000129550
ENSMUST00000134604
ENSMUST00000173376 ENSMUSP00000133468
ENSMUST00000174831 ENSMUSP00000133328
ENSMUST00000174023 ENSMUSP00000133562
ENSMUST00000174531 ENSMUSP00000134229
ENSMUST00000174180 ENSMUSP00000133973
ENSMUST00000173560
ENSMUST00000173662 ENSMUSP00000133832
ENSMUST00000172811 ENSMUSP00000134190
ENSMUST00000174832 ENSMUSP00000133580
ENSMUST00000173592
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0016791 phosphatase activity
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0006470 protein dephosphorylation
GO:0007157 heterophilic cell-cell adhesion
GO:0016311 dephosphorylation
GO:0030182 neuron differentiation
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0050775 positive regulation of dendrite morphogenesis
GO:0097105 presynaptic membrane assembly
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000153707
View Gene Order
ENSBTAG00000010178
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.146764 Mm.184021 Mm.403663 Mm.412168 Mm.420824 Mm.448387 Mm.472233 Mm.477158 Mm.489057 Mm.489068
RefSeq NM_001014288 NM_011211 XM_006537692 XM_006537693 XM_006537694 XM_006537695 XM_006537696 XM_006537698 XM_006537701 XM_006537702 XM_006537703
OMIM
CCDS CCDS57280
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca