InnateDB Protein
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IDBP-267227.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Etv4
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Protein Name
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ets variant gene 4 (E1A enhancer binding protein, E1AF)
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Synonyms
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AW414408; Pea-3; Pea3;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000102794
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InnateDB Gene
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IDBG-212373 (Etv4)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
4
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
11 [view]
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|
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Molecular Function |
Accession |
GO Term |
GO:0000981
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sequence-specific DNA binding RNA polymerase II transcription factor activity
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GO:0003677
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DNA binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0043565
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sequence-specific DNA binding
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Biological Process |
GO:0006355
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regulation of transcription, DNA-templated
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GO:0006357
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regulation of transcription from RNA polymerase II promoter
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GO:0006366
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transcription from RNA polymerase II promoter
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GO:0008045
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motor neuron axon guidance
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GO:0033600
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negative regulation of mammary gland epithelial cell proliferation
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GO:0045893
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positive regulation of transcription, DNA-templated
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GO:0048863
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stem cell differentiation
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GO:0060444
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branching involved in mammary gland duct morphogenesis
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GO:0060762
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regulation of branching involved in mammary gland duct morphogenesis
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|
Cellular Component |
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PDB ID |
MGI:99423
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InterPro |
IPR000418
Ets domain
IPR006715
PEA3-type ETS-domain transcription factor, N-terminal
|
PFAM |
PF00178
PF04621
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PRINTS |
PR00454
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PIRSF |
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SMART |
SM00413
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TIGRFAMs |
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Modification |
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SwissProt |
|
PhosphoSite |
PhosphoSite-
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TrEMBL |
A6MDC6
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UniProt Splice Variant |
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Entrez Gene |
18612
|
UniGene |
Mm.5025
|
RefSeq |
XP_006532523
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MGI ID |
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MGI Symbol |
Etv4
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AL591436
DQ832277
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GenPept |
ABI30211
|
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