|
InnateDB Protein
|
IDBP-267255.5
|
|
Last Modified
|
2012-02-14 [Report errors or provide feedback]
|
|
Gene Symbol
|
Arnt
|
|
Protein Name
|
aryl hydrocarbon receptor nuclear translocator
|
|
Synonyms
|
bHLHe2; D3Ertd557e; Drnt; ESTM42; Hif1b; mKIAA4051; W08714;
|
|
Species
|
Mus musculus
|
|
Ensembl Protein
|
ENSMUSP00000102778
|
|
InnateDB Gene
|
IDBG-172688 (Arnt)
|
|
Protein Structure
|
|
| Function |
|
| Subcellular Localization |
|
| Disease Associations |
|
| Tissue Specificity |
|
| Comments |
|
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 45 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
24
[view]
|
| Protein-Protein |
21
[view]
|
| Protein-DNA |
3
[view]
|
| Protein-RNA |
0
|
| DNA-DNA |
0
|
| RNA-RNA |
0
|
| DNA-RNA |
0
|
|
| Predicted by orthology |
| Total |
45 [view]
|
|
|
Molecular Function |
| Accession |
GO Term |
|
GO:0000989
|
transcription factor binding transcription factor activity
|
|
GO:0003677
|
DNA binding
|
|
GO:0003700
|
sequence-specific DNA binding transcription factor activity
|
|
GO:0003705
|
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
|
|
GO:0003713
|
transcription coactivator activity
|
|
GO:0004874
|
aryl hydrocarbon receptor activity
|
|
GO:0005515
|
protein binding
|
|
GO:0017162
|
aryl hydrocarbon receptor binding
|
|
GO:0035326
|
enhancer binding
|
|
GO:0043565
|
sequence-specific DNA binding
|
|
GO:0046982
|
protein heterodimerization activity
|
|
| Biological Process |
|
GO:0001666
|
response to hypoxia
|
|
GO:0001892
|
embryonic placenta development
|
|
GO:0006366
|
transcription from RNA polymerase II promoter
|
|
GO:0009636
|
response to toxic substance
|
|
GO:0010575
|
positive regulation vascular endothelial growth factor production
|
|
GO:0030154
|
cell differentiation
|
|
GO:0030522
|
intracellular receptor signaling pathway
|
|
GO:0043619
|
regulation of transcription from RNA polymerase II promoter in response to oxidative stress
|
|
GO:0045893
|
positive regulation of transcription, DNA-templated
|
|
GO:0045944
|
positive regulation of transcription from RNA polymerase II promoter
|
|
GO:0046886
|
positive regulation of hormone biosynthetic process
|
|
| Cellular Component |
|
| PDB ID |
MGI:88071
|
| InterPro |
|
| PFAM |
|
| PRINTS |
|
| PIRSF |
|
| SMART |
|
| TIGRFAMs |
|
| Modification |
|
| SwissProt |
|
| PhosphoSite |
PhosphoSite-
|
| TrEMBL |
D3YV20
|
| UniProt Splice Variant |
|
| Entrez Gene |
11863
|
| UniGene |
Mm.408872
|
| RefSeq |
|
| MGI ID |
|
| MGI Symbol |
Arnt
|
| OMIM |
|
| CCDS |
|
| HPRD |
|
| IMGT |
|
| EMBL |
AC092202
AC092203
|
| GenPept |
|
|
|
|
Version 5.4