Mus musculus Protein: Sox6
Summary
InnateDB Protein IDBP-268400.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sox6
Protein Name SRY-box containing gene 6
Synonyms AI987981; SOX-LZ;
Species Mus musculus
Ensembl Protein ENSMUSP00000102223
InnateDB Gene IDBG-207342 (Sox6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0000902 cell morphogenesis
GO:0001701 in utero embryonic development
GO:0006355 regulation of transcription, DNA-templated
GO:0009791 post-embryonic development
GO:0010468 regulation of gene expression
GO:0016458 gene silencing
GO:0021778 oligodendrocyte cell fate specification
GO:0030097 hemopoiesis
GO:0030218 erythrocyte differentiation
GO:0042692 muscle cell differentiation
GO:0045165 cell fate commitment
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048709 oligodendrocyte differentiation
GO:0048821 erythrocyte development
GO:0051216 cartilage development
GO:0055007 cardiac muscle cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID MGI:98368
InterPro IPR009071 High mobility group box domain
PFAM PF00505
PF09011
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8BSS6
UniProt Splice Variant
Entrez Gene 20679
UniGene Mm.471373
RefSeq NP_001020731
MGI ID
MGI Symbol Sox6
OMIM
CCDS CCDS40097
HPRD
IMGT
EMBL AC102696 AC107371 AC111041 AC118676 AC158579 AC158947 AK030713
GenPept BAC27094