InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vav3

Summary

InnateDB Protein

IDBP-268474.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Vav3

Protein Name

vav 3 oncogene

Synonyms

A530094I06Rik; AA986410; Idd18.1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000102186

InnateDB Gene

IDBG-188386 (Vav3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0005154	epidermal growth factor receptor binding
GO:0005515	protein binding
GO:0030676	Rac guanyl-nucleotide exchange factor activity
GO:0046872	metal ion binding

Biological Process

GO:0001525	angiogenesis
GO:0006906	vesicle fusion
GO:0006974	cellular response to DNA damage stimulus
GO:0007229	integrin-mediated signaling pathway
GO:0007264	small GTPase mediated signal transduction
GO:0016477	cell migration
GO:0030031	cell projection assembly
GO:0030032	lamellipodium assembly
GO:0030593	neutrophil chemotaxis
GO:0030890	positive regulation of B cell proliferation
GO:0032314	regulation of Rac GTPase activity
GO:0032319	regulation of Rho GTPase activity
GO:0042493	response to drug
GO:0043087	regulation of GTPase activity
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
GO:0045785	positive regulation of cell adhesion
GO:0050853	B cell receptor signaling pathway