InnateDB Protein
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IDBP-26867.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ICAM4
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Protein Name
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intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
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Synonyms
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CD242; LW;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000370147
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InnateDB Gene
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IDBG-26863 (ICAM4)
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Protein Structure
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Function |
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins. {ECO:0000269PubMed:11435317}.
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Subcellular Localization |
Isoform Long: Cell membrane; Single-pass type I membrane protein.Isoform Short: Secreted.
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Disease Associations |
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Tissue Specificity |
Erythrocytes.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003987
Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
IPR013768
Intercellular adhesion molecule, N-terminal
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PFAM |
PF03921
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PRINTS |
PR01472
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q14773
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
3386
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UniGene |
Hs.706750
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RefSeq |
NP_001535
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HUGO |
HGNC:5347
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OMIM |
614088
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CCDS |
CCDS12232
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HPRD |
00198
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IMGT |
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EMBL |
AC011511
BC000046
BC029364
BT009816
CH471106
DQ011692
L27670
L27671
S78852
X93093
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GenPept |
AAA59537
AAA59538
AAB35046
AAH00046
AAH29364
AAP88818
AAY16986
CAA63646
EAW84089
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