Version 5.4
Mus musculus Protein: Hsd3b7
Summary
InnateDB Protein IDBP-269113.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Hsd3b7
Protein Name hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
Synonyms AI195443; BB098564;
Species Mus musculus
Ensembl Protein ENSMUSP00000101879
InnateDB Gene IDBG-210381 (Hsd3b7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0008831 dTDP-4-dehydrorhamnose reductase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050662 coenzyme binding
Biological Process
GO:0006694 steroid biosynthetic process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0045226 extracellular polysaccharide biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID MGI:2141879
InterPro IPR001509 NAD-dependent epimerase/dehydratase
IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase
IPR003869 Polysaccharide biosynthesis protein, CapD-like domain
IPR005913 dTDP-4-dehydrorhamnose reductase
IPR008030 NmrA-like
IPR013120 Male sterility, NAD-binding
IPR013968 Polyketide synthase, KR
PFAM PF01370
PF00106
PF01073
PF02719
PF04321
PF05368
PF07993
PF08659
PRINTS PR00080
PIRSF PIRSF000126
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z3X1
UniProt Splice Variant
Entrez Gene 101502
UniGene Mm.486340
RefSeq
MGI ID
MGI Symbol Hsd3b7
OMIM
CCDS
HPRD
IMGT
EMBL AC149222
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca