Version 5.4
Mus musculus Protein: Cap1
Summary
InnateDB Protein IDBP-269149.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cap1
Protein Name CAP, adenylate cyclase-associated protein 1 (yeast)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000101864
InnateDB Gene IDBG-184645 (Cap1)
Protein Structure
UniProt Annotation
Function Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0000902 cell morphogenesis
GO:0001667 ameboidal cell migration
GO:0006898 receptor-mediated endocytosis
GO:0007010 cytoskeleton organization
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0030864 cortical actin cytoskeleton
Protein Structure and Domains
PDB ID MGI:88262
InterPro IPR006599 CARP motif
IPR013912 Adenylate cyclase-associated CAP, C-terminal
IPR013992 Adenylate cyclase-associated CAP, N-terminal
PFAM PF08603
PF01213
PRINTS
PIRSF
SMART SM00673
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P40124
PhosphoSite PhosphoSite-P40124
TrEMBL B1ARS0
UniProt Splice Variant
Entrez Gene 12331
UniGene Mm.8687
RefSeq XP_006502758
MGI ID
MGI Symbol Cap1
OMIM
CCDS CCDS18604
HPRD
IMGT
EMBL AK053351 AL606906 BC005446 BC005472 BX545849 L12367
GenPept AAC37610 AAH05446 AAH05472 BAC35357 CAM13994 CAM18197

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca