InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Uros

Summary

InnateDB Protein

IDBP-269380.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Uros

Protein Name

uroporphyrinogen III synthase

Synonyms

AI415298; UROIIIS; Uros3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101750

InnateDB Gene

IDBG-211247 (Uros)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004852	uroporphyrinogen-III synthase activity
GO:0048037	cofactor binding

Biological Process

GO:0006779	porphyrin-containing compound biosynthetic process
GO:0006780	uroporphyrinogen III biosynthetic process
GO:0033014	tetrapyrrole biosynthetic process
GO:0046677	response to antibiotic
GO:0071243	cellular response to arsenic-containing substance
GO:0071418	cellular response to amine stimulus

Cellular Component

GO:0005739	mitochondrion
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

MGI:98917

InterPro

IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase

PFAM

PF02602

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q9JLU5

UniProt Splice Variant

Entrez Gene

22276

UniGene

Mm.407149

RefSeq

XP_006507647

MGI ID

MGI Symbol

Uros

OMIM

CCDS

HPRD

IMGT

EMBL

AC127348 AF133258 AK002971 AK164297 CH466531

GenPept

AAF29593 BAB22486 BAE37723 EDL17771