Mus musculus Protein: Ptgfr
Summary
InnateDB Protein IDBP-269416.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptgfr
Protein Name prostaglandin F receptor
Synonyms AI957154; fp; PGF;
Species Mus musculus
Ensembl Protein ENSMUSP00000101732
InnateDB Gene IDBG-199872 (Ptgfr)
Protein Structure
UniProt Annotation
Function Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004958 prostaglandin F receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0032496 response to lipopolysaccharide
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:97796
InterPro IPR000141 Prostaglandin F receptor
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001105 Thromboxane receptor
IPR001244 Prostaglandin DP receptor
IPR008365 Prostanoid receptor
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00855
PR00237
PR00429
PR00428
PR01788
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P43117
PhosphoSite PhosphoSite-
TrEMBL Q8BNT7
UniProt Splice Variant
Entrez Gene 19220
UniGene Mm.331442
RefSeq
MGI ID
MGI Symbol Ptgfr
OMIM
CCDS CCDS17913
HPRD
IMGT
EMBL AB073966 AB094411 AK080620 AK087833 AK141760 BC064794 CH466532 D17433
GenPept AAH64794 BAA04251 BAC37962 BAC40021 BAC80245 BAC80246 BAE24824 EDL11940 EDL11941