Version 5.4
Mus musculus Protein: Yars
Summary
InnateDB Protein IDBP-269560.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Yars
Protein Name tyrosyl-tRNA synthetase
Synonyms AL024047; AU018965;
Species Mus musculus
Ensembl Protein ENSMUSP00000101669
InnateDB Gene IDBG-190620 (Yars)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004831 tyrosine-tRNA ligase activity
GO:0005524 ATP binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006437 tyrosyl-tRNA aminoacylation
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2147627
InterPro IPR002305 Aminoacyl-tRNA synthetase, class Ic
IPR002307 Tyrosine-tRNA ligase
IPR002547 tRNA-binding domain
IPR012340 Nucleic acid-binding, OB-fold
PFAM PF00579
PF01588
PRINTS PR01040
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91WQ3
PhosphoSite PhosphoSite-Q91WQ3
TrEMBL A2A7S7
UniProt Splice Variant
Entrez Gene 107271
UniGene Mm.415577
RefSeq NP_598912
MGI ID
MGI Symbol Yars
OMIM
CCDS CCDS18685
HPRD
IMGT
EMBL AK028785 AK043837 AK076634 AK139579 AK145356 AK151880 AK169708 AL606977 BC013552 BC022143 BC026615 CH466552
GenPept AAH13552 AAH22143 AAH26615 BAC26120 BAC31674 BAC36424 BAE24073 BAE26384 BAE30766 BAE41320 EDL30209

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca