Version 5.4
Mus musculus Protein: Dhdds
Summary
InnateDB Protein IDBP-269909.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dhdds
Protein Name dehydrodolichyl diphosphate synthase
Synonyms 3222401G21Rik; CIT; DS; HDS; W91638;
Species Mus musculus
Ensembl Protein ENSMUSP00000101511
InnateDB Gene IDBG-195542 (Dhdds)
Protein Structure
UniProt Annotation
Function Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=colocalizes with calnexin. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0006486 protein glycosylation
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005789 endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID MGI:1914672
InterPro IPR001441 Decaprenyl diphosphate synthase-like
PFAM PF01255
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99KU1
PhosphoSite PhosphoSite-Q99KU1
TrEMBL
UniProt Splice Variant
Entrez Gene 67422
UniGene Mm.472635
RefSeq
MGI ID
MGI Symbol Dhdds
OMIM
CCDS
HPRD
IMGT
EMBL AK034277 AK036929 AK049991 AK135087 AK149138 AK171207 AL670680 AL837508 BC004011
GenPept AAH04011 BAC28657 BAC29643 BAC34020 BAE22416 BAE28748 BAE42313 CAM46083

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca