Version 5.4
Mus musculus Gene: Dhdds
Summary
InnateDB Gene IDBG-195542.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dhdds
Gene Name dehydrodolichyl diphosphate synthase
Synonyms 3222401G21Rik; CIT; DS; HDS; W91638
Species Mus musculus
Ensembl Gene ENSMUSG00000012117
Encoded Proteins
IDBP-195544
dehydrodolichyl diphosphate synthase
IDBP-269907
dehydrodolichyl diphosphate synthase
IDBP-269909
dehydrodolichyl diphosphate synthase
IDBP-269911
dehydrodolichyl diphosphate synthase
IDBP-269913
dehydrodolichyl diphosphate synthase
IDBP-533529
dehydrodolichyl diphosphate synthase
IDBP-541892
dehydrodolichyl diphosphate synthase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117682:
The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:133969028-134000918
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000012262 ENSMUSP00000012262
ENSMUST00000105889 ENSMUSP00000101512
ENSMUST00000105887 ENSMUSP00000101511
ENSMUST00000105886 ENSMUSP00000101510
ENSMUST00000105885 ENSMUSP00000101509
ENSMUST00000144668 ENSMUSP00000116098
ENSMUST00000134096
ENSMUST00000142660
ENSMUST00000146241
ENSMUST00000130464 ENSMUSP00000121656
ENSMUST00000150729
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0006486 protein glycosylation
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005789 endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000117682
View Gene Order
ENSBTAG00000003235
Not yet available
Pathways
NETPATH
REACTOME
REACT_248642
Synthesis of substrates in N-glycan biosythesis pathway
REACT_202113
Synthesis of Dolichyl-phosphate pathway
REACT_262413
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_237472
Asparagine N-linked glycosylation pathway
KEGG
mmu00900
Terpenoid backbone biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22230
Synthesis of Dolichyl-phosphate pathway
REACT_22433
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_22387
Synthesis of substrates in N-glycan biosythesis pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa00900
Terpenoid backbone biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.410023 Mm.472635
RefSeq NM_026144
OMIM
CCDS CCDS18760
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca