InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rere

Summary

InnateDB Protein

IDBP-270359.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rere

Protein Name

arginine glutamic acid dipeptide (RE) repeats

Synonyms

1110033A15Rik; AI414665; ARG; ARP; ATN1L; Atr2; AW742570; DNB1; eye; eyes3; mKIAA0458;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101307

InnateDB Gene

IDBG-205779 (Rere)

Protein Structure

UniProt Annotation

Function

Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. {ECO:0000269PubMed:14645126}.

Subcellular Localization

Nucleus, PML body {ECO:0000250}. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	4 [view]
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006338	chromatin remodeling
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development

Cellular Component

GO:0000118	histone deacetylase complex
GO:0005739	mitochondrion
GO:0016605	PML body

Protein Structure and Domains

PDB ID

MGI:2683486

InterPro

IPR000679 Zinc finger, GATA-type
IPR000949 ELM2 domain
IPR001005 SANT/Myb domain
IPR001025 Bromo adjacent homology (BAH) domain
IPR002951 Atrophin-like
IPR009057 Homeodomain-like

PFAM

PF00320
PF01448
PF00249
PF01426
PF03154

PRINTS

PR00619

PIRSF

SMART

SM00401
SM00717
SM00439

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt