InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mbd3

Summary

InnateDB Protein

IDBP-271069.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Mbd3

Protein Name

methyl-CpG binding domain protein 3

Synonyms

AI181826; AU019209;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000100984

InnateDB Gene

IDBG-174078 (Mbd3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.

Experimentally validated
Total	28 [view]
Protein-Protein	28 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	50 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0005515	protein binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001701	in utero embryonic development
GO:0006346	methylation-dependent chromatin silencing
GO:0009888	tissue development
GO:0016573	histone acetylation

Cellular Component

GO:0000785	chromatin
GO:0000792	heterochromatin
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016581	NuRD complex
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

MGI:1333812

InterPro

IPR001739 Methyl-CpG DNA binding
IPR016177 DNA-binding domain

PFAM

PF01429

PRINTS

PIRSF

SMART

SM00391

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3YTR5

UniProt Splice Variant

Entrez Gene

17192

UniGene

Mm.7142

RefSeq

MGI ID

MGI Symbol

Mbd3

OMIM

CCDS

HPRD

IMGT

EMBL

AC152062

GenPept