InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mos

Summary

InnateDB Protein

IDBP-271530.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mos

Protein Name

Moloney sarcoma oncogene

Synonyms

c-mos;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000100789

InnateDB Gene

IDBG-271528 (Mos)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed specifically in testis during spermatogenesis.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004709	MAP kinase kinase kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0000165	MAPK cascade
GO:0000186	activation of MAPKK activity
GO:0000187	activation of MAPK activity
GO:0000212	meiotic spindle organization
GO:0006325	chromatin organization
GO:0006468	protein phosphorylation
GO:0040020	regulation of meiosis
GO:0046777	protein autophosphorylation
GO:0051296	establishment of meiotic spindle orientation
GO:1902103	negative regulation of metaphase/anaphase transition of meiotic cell cycle

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:97052

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt