InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ahr

Summary

InnateDB Protein

IDBP-274134.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Ahr

Protein Name

aryl-hydrocarbon receptor

Synonyms

Ah; Ahh; Ahre; bHLHe76; In;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112137

InnateDB Gene

IDBG-134957 (Ahr)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	9 [view]
Protein-DNA	8 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	41 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0004871	signal transducer activity
GO:0004879	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0035326	enhancer binding
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding
GO:0046983	protein dimerization activity
GO:0051879	Hsp90 protein binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0006805	xenobiotic metabolic process
GO:0006950	response to stress
GO:0007165	signal transduction
GO:0009410	response to xenobiotic stimulus
GO:0010468	regulation of gene expression
GO:0030522	intracellular receptor signaling pathway
GO:0030850	prostate gland development
GO:0030888	regulation of B cell proliferation
GO:0045087	innate immune response (InnateDB)
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0048608	reproductive structure development
GO:0048732	gland development