InnateDB Protein
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IDBP-27716.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SEC11A
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Protein Name
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SEC11 homolog A (S. cerevisiae)
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Synonyms
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1810012E07Rik; SEC11L1; sid2895; SPC18; SPCS4A;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000268220
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InnateDB Gene
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IDBG-27714 (SEC11A)
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Protein Structure
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Function |
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}.
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Subcellular Localization |
Microsome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
9
[view]
|
Protein-Protein |
7
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001733
Peptidase S26B, eukaryotic signal peptidase
IPR015927
Peptidase S24/S26A/S26B/S26C
IPR019759
Peptidase S24/S26A/S26B
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PFAM |
PF00717
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PRINTS |
PR00728
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P67812
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PhosphoSite |
PhosphoSite-P67812
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TrEMBL |
H0YNX5
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UniProt Splice Variant |
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Entrez Gene |
23478
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UniGene |
Hs.9534
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RefSeq |
NP_055115
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HUGO |
HGNC:17718
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OMIM |
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CCDS |
CCDS45340
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HPRD |
07503
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IMGT |
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EMBL |
AC087732
AC115102
AF061737
AF090315
AF108945
AK223224
AK300693
AK314146
BC000359
BC014508
CH471101
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GenPept |
AAC36354
AAD17526
AAD19640
AAH00359
AAH14508
BAD96944
BAG36834
BAG62376
EAX01952
EAX01954
EAX01955
EAX01956
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