InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ADAMTS20

Summary

InnateDB Protein

IDBP-27899.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADAMTS20

Protein Name

ADAM metallopeptidase with thrombospondin type 1 motif, 20

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000374071

InnateDB Gene

IDBG-27897 (ADAMTS20)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004175	endopeptidase activity
GO:0004222	metalloendopeptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0009967	positive regulation of signal transduction
GO:0030198	extracellular matrix organization
GO:0043066	negative regulation of apoptotic process
GO:0045636	positive regulation of melanocyte differentiation
GO:0048070	regulation of developmental pigmentation

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005615	extracellular space
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

InterPro

IPR000884 Thrombospondin, type 1 repeat
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR002870 Peptidase M12B, propeptide
IPR010294 ADAM-TS Spacer 1
IPR012314 Peptidase M12B, GON-ADAMTSs
IPR013273 Peptidase M12B, ADAM-TS

PFAM

PF00090
PF01421
PF01562
PF05986
PF08685

PRINTS

PR01857

PIRSF

SMART

SM00209

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt