InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RUNX1T1

Summary

InnateDB Protein

IDBP-28422.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RUNX1T1

Protein Name

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

Synonyms

AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2;

Species

Homo sapiens

Ensembl Protein

ENSP00000353504

InnateDB Gene

IDBG-28420 (RUNX1T1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 68 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	68 [view]
Protein-Protein	67 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0042802	identical protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006091	generation of precursor metabolites and energy
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated

Cellular Component

GO:0016363

nuclear matrix

Protein Structure and Domains

PDB ID

InterPro

IPR002893 Zinc finger, MYND-type
IPR003894 TAFH/NHR1
IPR013289 Eight-Twenty-One
IPR013290 Myeloid transforming gene on chromosome 8 (MTG8)
IPR014896 NHR2-like

PFAM

PF01753
PF07531
PF08788

PRINTS

PR01875
PR01876

PIRSF

SMART

SM00549

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt