InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NUFIP1

Summary

InnateDB Protein

IDBP-28960.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NUFIP1

Protein Name

nuclear fragile X mental retardation protein interacting protein 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000368459

InnateDB Gene

IDBG-28958 (NUFIP1)

Protein Structure

UniProt Annotation

Function

Binds RNA. {ECO:0000269PubMed:10556305}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:10556305}. Note=Distributed in the nucleus in a dot-like pattern.

Disease Associations

Tissue Specificity

Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. {ECO:0000269PubMed:10556305}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.

Experimentally validated
Total	26 [view]
Protein-Protein	23 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0030515	snoRNA binding
GO:0030674	protein binding, bridging
GO:0042802	identical protein binding
GO:0046872	metal ion binding

Biological Process

GO:0000492	box C/D snoRNP assembly
GO:0006396	RNA processing
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0005726	perichromatin fibrils
GO:0005730	nucleolus
GO:0008023	transcription elongation factor complex
GO:0016363	nuclear matrix
GO:0022626	cytosolic ribosome
GO:0048786	presynaptic active zone
GO:0070761	pre-snoRNP complex