InnateDB Protein
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IDBP-29074.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ATP6V1C2
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Protein Name
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ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000371077
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InnateDB Gene
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IDBG-29072 (ATP6V1C2)
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Protein Structure
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Function |
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Kidney and placenta. {ECO:0000269PubMed:12384298}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0015078
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hydrogen ion transmembrane transporter activity
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GO:0046983
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protein dimerization activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004907
ATPase, V1 complex, subunit C
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PFAM |
PF03223
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NEY4
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PhosphoSite |
PhosphoSite-Q8NEY4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
245973
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UniGene |
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RefSeq |
NP_653184
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HUGO |
HGNC:18264
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OMIM |
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CCDS |
CCDS1674
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HPRD |
16523
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IMGT |
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EMBL |
AC092687
AY039759
BC012142
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GenPept |
AAH12142
AAK83464
AAY24069
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