InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PDIA6

Summary

InnateDB Protein

IDBP-29166.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PDIA6

Protein Name

protein disulfide isomerase family A, member 6

Synonyms

ERP5; P5; TXNDC7;

Species

Homo sapiens

Ensembl Protein

ENSP00000371024

InnateDB Gene

IDBG-29164 (PDIA6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 71 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	71 [view]
Protein-Protein	71 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003756	protein disulfide isomerase activity
GO:0005515	protein binding
GO:0016853	isomerase activity

Biological Process

GO:0006457	protein folding
GO:0006987	activation of signaling protein activity involved in unfolded protein response
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0034976	response to endoplasmic reticulum stress
GO:0043277	apoptotic cell clearance
GO:0044267	cellular protein metabolic process
GO:0045454	cell redox homeostasis

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen
GO:0005789	endoplasmic reticulum membrane
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
GO:0005886	plasma membrane
GO:0042470	melanosome
GO:0070062	extracellular vesicular exosome