InnateDB Protein
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IDBP-292365.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CCNL2
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Protein Name
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cyclin L2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000386158
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InnateDB Gene
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IDBG-281455 (CCNL2)
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Protein Structure
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Function |
Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the expression of critical apoptotic factor, leading to cell apoptosis. {ECO:0000269PubMed:14684736}.
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Subcellular Localization |
Nucleus speckle {ECO:0000269PubMed:14684736}.
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Disease Associations |
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Tissue Specificity |
Ubiquitously expressed, with a higher expression level observed in ovary, heart, liver and pancreas. {ECO:0000269PubMed:14684736}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0019901
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protein kinase binding
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Biological Process |
GO:0000079
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regulation of cyclin-dependent protein serine/threonine kinase activity
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GO:0006351
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transcription, DNA-templated
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GO:0006355
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regulation of transcription, DNA-templated
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GO:0006396
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RNA processing
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Cellular Component |
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PDB ID |
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InterPro |
IPR006671
Cyclin, N-terminal
IPR013763
Cyclin-like
IPR017060
Cyclin L
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PFAM |
PF00134
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PRINTS |
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PIRSF |
PIRSF036580
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SMART |
SM00385
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TIGRFAMs |
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Modification |
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SwissProt |
Q96S94
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PhosphoSite |
PhosphoSite-Q96S94
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TrEMBL |
J3QSH2
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UniProt Splice Variant |
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Entrez Gene |
81669
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UniGene |
Hs.735359
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RefSeq |
NP_001034666
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HUGO |
HGNC:20570
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OMIM |
613482
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CCDS |
CCDS30558
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HPRD |
10815
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IMGT |
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EMBL |
AF087903
AK027770
AK074112
AK292268
AL391244
AL834432
AL834441
AY037150
AY116620
BC016333
BC071622
CH471183
CR628411
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GenPept |
AAH16333
AAH71622
AAK67631
AAM76789
AAP97201
BAB84938
BAF84957
BAG51376
CAD39092
CAD39101
CAI22659
CAI22660
CAM12829
EAW56213
EAW56216
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