InnateDB Protein
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IDBP-292373.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ING5
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Protein Name
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inhibitor of growth family, member 5
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000385937
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InnateDB Gene
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IDBG-85288 (ING5)
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Protein Structure
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Function |
Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator. {ECO:0000269PubMed:12750254, ECO:0000269PubMed:16387653}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:18794358}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
47
[view]
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Protein-Protein |
47
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR011011
Zinc finger, FYVE/PHD-type
IPR019787
Zinc finger, PHD-finger
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PFAM |
PF00628
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8WYH8
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PhosphoSite |
PhosphoSite-Q8WYH8
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
84289
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UniGene |
Hs.667169
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RefSeq |
XP_005247104
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HUGO |
HGNC:19421
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OMIM |
608525
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CCDS |
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HPRD |
16348
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IMGT |
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EMBL |
AC114730
AC133528
AF189286
AK074422
AK289958
BC005370
BC071899
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GenPept |
AAH05370
AAH71899
AAL68979
AAX82019
AAY14921
BAB85078
BAF82647
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