Version 5.4
Homo sapiens Protein: PPM1B
Summary
InnateDB Protein IDBP-293716.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPM1B
Protein Name protein phosphatase, Mg2+/Mn2+ dependent, 1B
Synonyms PP2C-beta; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX;
Species Homo sapiens
Ensembl Protein ENSP00000386982
InnateDB Gene IDBG-49488 (PPM1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 50 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 50 [view]
Protein-Protein 49 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0030145 manganese ion binding
Biological Process
GO:0006470 protein dephosphorylation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001932 Protein phosphatase 2C (PP2C)-like domain
IPR012911 Protein serine/threonine phosphatase 2C, C-terminal
PFAM PF00481
PF07228
PF07830
PRINTS
PIRSF
SMART SM00331
SM00332
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B8ZZF0
UniProt Splice Variant
Entrez Gene 5495
UniGene Hs.713776
RefSeq
HUGO HGNC:9276
OMIM 603770
CCDS
HPRD 04796
IMGT
EMBL AC013717 AC019129
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca