InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SYNC

Summary

InnateDB Protein

IDBP-293926.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SYNC

Protein Name

syncoilin, intermediate filament protein

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000386439

InnateDB Gene

IDBG-95790 (SYNC)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm, perinuclear region {ECO:0000250UniProtKB:Q9EPM5}. Note=In skeletal muscle, colocalizes with DES and DTNA, and is localized at the myotendinous and neuromuscular junctions, sarcolemma and Z-lines. In myotubes, detected in a punctate cytoplasmic pattern (By similarity). {ECO:0000250UniProtKB:Q9EPM5}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding

Biological Process

GO:0045103

intermediate filament-based process

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005882	intermediate filament
GO:0030018	Z disc
GO:0031594	neuromuscular junction
GO:0042383	sarcolemma
GO:0048471	perinuclear region of cytoplasm