InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MGAT5

Summary

InnateDB Protein

IDBP-294194.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MGAT5

Protein Name

mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase

Synonyms

GNT-V; GNT-VA;

Species

Homo sapiens

Ensembl Protein

ENSP00000386377

InnateDB Gene

IDBG-70492 (MGAT5)

Protein Structure

UniProt Annotation

Function

Catalyzes the addition of N-acetylglucosamine in beta 1- 6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides.

Subcellular Localization

Golgi apparatus membrane; Single-pass type II membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008375	acetylglucosaminyltransferase activity
GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

Biological Process

GO:0006487	protein N-linked glycosylation
GO:0018279	protein N-linked glycosylation via asparagine
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process