InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LSM5

Summary

InnateDB Protein

IDBP-294397.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LSM5

Protein Name

LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)

Synonyms

YER146W;

Species

Homo sapiens

Ensembl Protein

ENSP00000387109

InnateDB Gene

IDBG-11615 (LSM5)

Protein Structure

UniProt Annotation

Function

Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA, thereby facilitating formation of the spliceosomal U4/U6 duplex formation in vitro.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	28 [view]
Protein-Protein	25 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding

Biological Process

GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0006397	mRNA processing
GO:0008380	RNA splicing
GO:0010467	gene expression
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay