Version 5.4
Homo sapiens Protein: CLEC16A
Summary
InnateDB Protein IDBP-294426.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC16A
Protein Name C-type lectin domain family 16, member A
Synonyms Gop-1; KIAA0350;
Species Homo sapiens
Ensembl Protein ENSP00000386495
InnateDB Gene IDBG-14527 (CLEC16A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations Note=Insulin-dependent diabetes mellitus is significantly associated with variation within a 233-kb linkage disequilibrium block on chromosome 16p13 that includes KIAA0350. Three common non-coding variants of KIAA0350 in strong linkage disequilibrium reach genome-wide significance for association with the disease (PubMed:17632545). {ECO:0000269PubMed:17632545}.
Tissue Specificity Almost exclusively expressed in immune cells, including dendritic cells, B-lymphocytes and natural killer cells. {ECO:0000269PubMed:17632545}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Protein Structure and Domains
PDB ID
InterPro IPR019155 Uncharacterised protein family FPL
PFAM PF09758
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KHT3
PhosphoSite PhosphoSite-Q2KHT3
TrEMBL
UniProt Splice Variant
Entrez Gene 23274
UniGene Hs.606287
RefSeq NP_001230332
HUGO HGNC:29013
OMIM 611303
CCDS CCDS58423
HPRD 17185
IMGT
EMBL AB002348 AK126771 BC112897
GenPept AAI12898 BAA20807

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca