Version 5.4
Homo sapiens Protein: CEACAM1
Summary
InnateDB Protein IDBP-294535.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CEACAM1
Protein Name carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
Synonyms BGP; BGP1; BGPI;
Species Homo sapiens
Ensembl Protein ENSP00000384083
InnateDB Gene IDBG-54381 (CEACAM1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Isoform 1: Cell membrane; Single-pass type I membrane protein.Isoform 2: Secreted.Isoform 3: Secreted.Isoform 4: Secreted.Isoform 5: Cell membrane; Single-pass type I membrane protein.Isoform 6: Cell membrane; Single-pass type I membrane protein.Isoform 7: Cell membrane; Single-pass type I membrane protein.Isoform 8: Cell membrane; Single-pass type I membrane protein. Note=Localizes to sites of cell-cell contact.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0001525 angiogenesis
GO:0007156 homophilic cell adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0016477 cell migration
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
PFAM PF07679
PF07686
PF00047
PRINTS
PIRSF
SMART SM00408
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P13688
PhosphoSite PhosphoSite-P13688
TrEMBL M0R2K4
UniProt Splice Variant
Entrez Gene 634
UniGene Hs.604089
RefSeq NP_001171745
HUGO HGNC:1814
OMIM 109770
CCDS CCDS54272
HPRD 00191
IMGT
EMBL AC004559 AC004785 AC104105 AY766113 BC014473 CH471126 D12502 D90311 D90312 D90313 DQ989182 J03858 M69176 M72238 M76741 M76742 M76743 M76744 S71326 X14831 X16354 X16356 X67277
GenPept AAA51825 AAA51826 AAA57141 AAA57142 AAA57143 AAA57144 AAA58393 AAA58394 AAB31183 AAC18433 AAC18434 AAC18435 AAC18436 AAC18437 AAC18438 AAC18439 AAH14473 AAV34600 ABI75349 BAA02063 BAA14341 BAA14342 BAA14343 CAA32940 CAA34404 CAA34405 CAA47694 EAW57137 EAW57140 EAW57141 EAW57143

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca