Version 5.4
Homo sapiens Protein: DPYSL5
Summary
InnateDB Protein IDBP-294659.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DPYSL5
Protein Name dihydropyrimidinase-like 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000385549
InnateDB Gene IDBG-36183 (DPYSL5)
Protein Structure
UniProt Annotation
Function May have a function in neuronal differentiation and/or axon growth.
Subcellular Localization Cytoplasm {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Biological Process
GO:0006208 pyrimidine nucleobase catabolic process
GO:0007165 signal transduction
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR006680 Amidohydrolase 1
IPR011059 Metal-dependent hydrolase, composite domain
IPR011778 Hydantoinase/dihydropyrimidinase
PFAM PF01979
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BPU6
PhosphoSite PhosphoSite-Q9BPU6
TrEMBL Q53T73
UniProt Splice Variant
Entrez Gene 56896
UniGene Hs.299315
RefSeq NP_001240652
HUGO HGNC:20637
OMIM 608383
CCDS CCDS1730
HPRD 10522
IMGT
EMBL AC011740 AC013472 AF157634 AF264015 AJ251275 AL713706 BC002874 BT006871
GenPept AAF80348 AAH02874 AAK16830 AAP35517 AAX93268 AAY14652 CAB95124 CAD28503

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca