InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SDC2

Summary

InnateDB Protein

IDBP-29496.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SDC2

Protein Name

syndecan 2

Synonyms

CD362; HSPG; HSPG1; SYND2;

Species

Homo sapiens

Ensembl Protein

ENSP00000307046

InnateDB Gene

IDBG-29494 (SDC2)

Protein Structure

UniProt Annotation

Function

Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	32 [view]
Protein-Protein	31 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008092	cytoskeletal protein binding
GO:0030165	PDZ domain binding

Biological Process

GO:0001523	retinoid metabolic process
GO:0001666	response to hypoxia
GO:0005975	carbohydrate metabolic process
GO:0006024	glycosaminoglycan biosynthetic process
GO:0006027	glycosaminoglycan catabolic process
GO:0007603	phototransduction, visible light
GO:0008150	biological_process
GO:0030198	extracellular matrix organization
GO:0030203	glycosaminoglycan metabolic process
GO:0030204	chondroitin sulfate metabolic process
GO:0031000	response to caffeine
GO:0042060	wound healing
GO:0044281	small molecule metabolic process
GO:0048813	dendrite morphogenesis
GO:0048814	regulation of dendrite morphogenesis

Cellular Component

GO:0005796	Golgi lumen
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043025	neuronal cell body
GO:0043202	lysosomal lumen
GO:0045202	synapse