Version 5.4
Homo sapiens Protein: TFEB
Summary
InnateDB Protein IDBP-295013.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFEB
Protein Name transcription factor EB
Synonyms ALPHATFEB; BHLHE35; TCFEB;
Species Homo sapiens
Ensembl Protein ENSP00000383998
InnateDB Gene IDBG-86793 (TFEB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0046983 protein dimerization activity
Biological Process
GO:0001892 embryonic placenta development
GO:0006355 regulation of transcription, DNA-templated
GO:0006959 humoral immune response
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
IPR021802 Basic helix-loop-helix leucine zipper transcrition factor MiT/TFE
PFAM PF00010
PF11851
PRINTS
PIRSF
SMART SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B1AKB5
UniProt Splice Variant
Entrez Gene 7942
UniGene Hs.485360
RefSeq
HUGO HGNC:11753
OMIM 600744
CCDS
HPRD 02847
IMGT
EMBL AL035588 AL365205
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca