Version 5.4
Homo sapiens Gene: TFEB
Summary
InnateDB Gene IDBG-86793.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFEB
Gene Name transcription factor EB
Synonyms ALPHATFEB; BHLHE35; TCFEB
Species Homo sapiens
Ensembl Gene ENSG00000112561
Encoded Proteins
IDBP-86795
transcription factor EB
IDBP-86797
transcription factor EB
IDBP-86799
transcription factor EB
IDBP-86801
transcription factor EB
IDBP-241892
transcription factor EB
IDBP-295013
transcription factor EB
IDBP-295010
transcription factor EB
IDBP-378360
transcription factor EB
IDBP-378396
transcription factor EB
IDBP-378401
transcription factor EB
IDBP-378403
transcription factor EB
IDBP-378405
transcription factor EB
IDBP-378410
transcription factor EB
IDBP-378413
transcription factor EB
IDBP-378414
transcription factor EB
IDBP-378415
transcription factor EB
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:41683978-41736259
Strand Reverse strand
Band p21.1
Transcripts
ENST00000358871 ENSP00000351742
ENST00000230323 ENSP00000230323
ENST00000343317 ENSP00000343948
ENST00000373033 ENSP00000362124
ENST00000394283 ENSP00000377824
ENST00000406563 ENSP00000383998
ENST00000403298 ENSP00000384203
ENST00000420312 ENSP00000412551
ENST00000419396 ENSP00000410391
ENST00000416140 ENSP00000406491
ENST00000419574 ENSP00000400276
ENST00000424495 ENSP00000396168
ENST00000445214 ENSP00000393874
ENST00000425401 ENSP00000415035
ENST00000433032 ENSP00000415946
ENST00000445700 ENSP00000395208
ENST00000494822
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0046983 protein dimerization activity
Biological Process
GO:0001892 embryonic placenta development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006914 autophagy
GO:0006959 humoral immune response
GO:0007040 lysosome organization
GO:0010508 positive regulation of autophagy
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000023990
View Gene Order
ENSBTAG00000012384
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.485360
RefSeq NM_001167827 NM_001271943 NM_001271944 NM_001271945 NM_007162 XM_005249411 XM_005249412 XM_006715213
HUGO
OMIM
CCDS CCDS4858 CCDS64424 CCDS64425
HPRD 02847
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca