InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PEX11A

Summary

InnateDB Protein

IDBP-29522.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PEX11A

Protein Name

peroxisomal biogenesis factor 11 alpha

Synonyms

hsPEX11p; PEX11-ALPHA; PMP28;

Species

Homo sapiens

Ensembl Protein

ENSP00000300056

InnateDB Gene

IDBG-29520 (PEX11A)

Protein Structure

UniProt Annotation

Function

May be involved in peroxisomal proliferation and may regulate peroxisomes division. May mediate binding of coatomer proteins to the peroxisomal membrane. {ECO:0000269PubMed:9792670}.

Subcellular Localization

Peroxisome membrane {ECO:0000269PubMed:9714566, ECO:0000269PubMed:9792670}; Multi- pass membrane protein {ECO:0000269PubMed:9714566, ECO:0000269PubMed:9792670}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0007031	peroxisome organization
GO:0007165	signal transduction
GO:0016557	peroxisome membrane biogenesis
GO:0016559	peroxisome fission
GO:0044255	cellular lipid metabolic process
GO:0044281	small molecule metabolic process
GO:0044375	regulation of peroxisome size
GO:0050873	brown fat cell differentiation