InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: POLR1A

Summary

InnateDB Protein

IDBP-295359.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

POLR1A

Protein Name

polymerase (RNA) I polypeptide A, 194kDa

Synonyms

A190; RPA1; RPA194; RPO1-4; RPO14;

Species

Homo sapiens

Ensembl Protein

ENSP00000386300

InnateDB Gene

IDBG-59571 (POLR1A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	44 [view]
Protein-Protein	41 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003899	DNA-directed RNA polymerase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006351

transcription, DNA-templated

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000722 RNA polymerase, alpha subunit
IPR006592 RNA polymerase, N-terminal
IPR007066 RNA polymerase Rpb1, domain 3
IPR007080 RNA polymerase Rpb1, domain 1
IPR007081 RNA polymerase Rpb1, domain 5
IPR007083 RNA polymerase Rpb1, domain 4

PFAM

PF00623
PF04983
PF04997
PF04998
PF05000

PRINTS

PIRSF

SMART

SM00663

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite